PhD Recruitment Process2026-10-05T09:04:33+01:00

The CRUK CoL Centre PhD Programme

Applications for the CRUK CoL Centre PhD programme starting in September 2027 are open

This is a unique multidisciplinary and collaborative training opportunity for graduates with a background in biological, biomedical or other relevant sciences, who are interested in carrying out research in cancer biotherapeutics.

Students accepted onto the programme will follow the four-year version of our PhD programme, benefitting from high quality multidisciplinary scientific & transferable skills training, and cohort-building & networking activities. In addition, you will develop a customised training plan together with your supervisor tailored to your background and project requirements.

We are looking for talented and motivated candidates, who are passionate about research and have a strong academic track record. You will be based in your primary supervisor’s research group, and you will have the opportunity to work across the Centre, for example when carrying out research placements or accessing the Centre’s infrastructure cores. These are full-time research positions fully funded for four years.

Eligibility criteria

Applicants must have obtained, or be about to obtain, a First or Upper Second Class UK Honours degree, or the equivalent qualifications gained outside the UK, in an area appropriate to the skills requirements of the Centre.

Applicants do not need to submit information relating to English language skills during the CoL Centre application process. If you are offered a PhD studentship you might require an English language qualification to apply at the host university.

The funding for this fellowship covers students with Home tuition fee status only. For more information on Home tuition fee status please visit the UKCISA website. Please note that we will only be able to offer studentships to candidates that have Home tuition fee status or provide evidence that they can fund the international portion of the tuition fee from external sources (i.e. not self-funded).

Funding

Studentships are sponsored fully for 4 years commencing September 2027. Funding covers:

  • A non-taxable annual stipend of £25,074 (incremental increase per year of 1.75%, current CRUK rate)
  • Tuition fees for Home status only (see section Eligibility criteria)
  • Generous consumable budget
  • Training & travel budget

Applications

Before beginning an application, you should read the information on this page and the “completing the application form” page. You should also find out about the projects being offered to start in September 2027 and their supervisors via the specific project pages below.

Key dates

  • Your application must be submitted by the deadline: 4 November 2026, noon
  • We should receive your references by  11 November 2026, noon. Your application may still be considered if references are not received by this deadline. However, no applicant will be invited to interview unless references have been received.
  • You will find out if you have been invited to interview for the programme before: 4 January 2027
  • Supervisors may contact you during the shortlisting period (late mid November to mid December), to find out more about you and your interest in their project.
  • Information session for interviewees: 4 January 2027, noon
  • Panel interviews will take place: w/c 11 January 2027
  • Programme start date:  September 2027

Interviews

During the interview, candidates will be interviewed by a panel of CRUK CoL Centre academics from across the Centre’s partners. Please note that not all projects will be funded and studentships will be awarded to the best applicants based on information submitted on the application form, references and performance during the interview.

PhD Projects available

Project 1: Roles of liver metabolism in breast cancer development and response to therapy

Primary supervisor: Dimitrios Anastasiou, UCL Co-supervisors: Ilaria Malanchi, Francis Crick Institute

Project 2: Adipocytes and breast cancer: a dangerous liaison

Primary supervisor: Katiuscia Bianchi, Queen Mary University of London Co-supervisor: Cheema Umber, UCL

Project 3: How does the PKCa-D463H oncogenic mutation drive epigenetic reprogramming and cancer?

Primary supervisor: Angus Cameron, Queen Mary University of London Co-supervisors: Neil McDonald, Francis Crick Institute

Project 4: Impact of mutant immune infiltrates on response to cancer immunotherapy

Primary supervisor: Francesca Ciccarelli, Queen Mary University of London Co-supervisor: Dominique Bonnet, Francis Crick Institute

Project 5: Transposable elements as a source of novel isoforms and immunotherapy targets in Paediatric Acute Myeloid Leukaemia

Primary supervisor: Özgen Deniz, Queen Mary University of London Co-supervisors: Richard Dillon, King’s College London

Project 6: Spatiotemporal mapping of hypoxia–immune–ECM interactions driving therapy resistance in MASH-associated hepatocellular carcinoma

Primary supervisor: Gilbert Fruhwirt, King’s College London Co-supervisor: Oscar Maiques, Queen Mary University of London

Project 7: AI-Enabled Engineering of Programmable Intracellular Biologics for Next-Generation Cancer Immunotherapy

Primary supervisor: Crispin Hiley, UCL Co-supervisor: Charlie McTernan, Francis Crick Institute; Sergio Quezada, UCL

Project 8: Deciphering the molecular determinants of pre-malignant mesothelial cell fitness to identify opportunities for cancer interception in pleural mesothelioma

Primary supervisor: Sam Janes, UCL Co-supervisor: Stuart McDonald, Queen Mary University of London

Project 9: AI-guided discovery of early cancer-associated epigenetic cell states from single-cell DNA methylation

Primary supervisor: Tommy Kaplan, Queen Mary University of London Co-supervisor: Simone Zaccaria, UCL

Project 10: Engineering shielded, bone marrow homing regulatory T cells for hypoplastic myelodysplastic neoplasms

Primary supervisor: Shahram Kordasti, King’s College London Co-supervisor: Sara Ghorashian, UCL

Project 11: How cancer telomere lengthening pathways shape chromosomal instability and tumour evolution

Primary supervisor: Sarah McClelland, Queen Mary University of London Co-supervisors: Simon Boulton, Francis Crick Institute

Project 12: Targeting noncanonical epitopes to develop novel immunotherapies for leukaemia

Primary supervisor: Michele Mishto, King’s College London Co-supervisor: Rob Sellar, UCL

Project 13: Dissecting the role of the choroid plexus in gliomagenesis

Primary supervisor: Simona Parinello, UCL Co-supervisors: Ilaria Malanchi, Francis Crick Institute; Laura Pellegrini, King’s College London

Project 14: Targeting tumour-specific T cell dysregulation to intercept lung cancer

Primary supervisor: James Reading, UCL Co-supervisor: Timothy Tree, King’s College London

Project 15: Further insights into the clinical impact of annual screening with a multicancer blood test: Data analysis from NHS-Galleri

Primary supervisor: Peter Sasieni, Queen Mary University of London Co-supervisor: Mieke Van Hemelrijck, King’s College London

Project 16: Exploiting nuclear envelope mislocalisation as an immunotherapeutic vulnerability in MYC-Driven Medulloblastoma

Primary supervisor: Sheila Singh, King’s College London Co-supervisor: John Anderson, UCL

Project 17: Genome-Wide CRISPR and Single-Cell Phenoscaping to Identify Universal Plasticity Regulators in Colorectal Cancer

Primary supervisor: Chris Tape, UCL Co-supervisor: Graeme Hewitt, King’s College London

Project 18: Developing Novel Immunotherapies for Paediatric Diffuse Midline Glioma

Primary supervisor: Richard Vile, King’s College London Co-supervisor: John Marshall, Queen Mary University of London

Project 19: Reprogramming vascular-immune interactions in human glioblastoma

Primary supervisor: Thomas Wälchli, UCL Co-supervisor: Kairbaan Hodivala-Dilke, Queen Mary University of London

Applications are open

For general enquiries regarding the CoL Centre training programme please email: iris.lueke@crick.ac.uk