MBPhD projects available for 2024 intake

Project 1: Understanding how initiating genetic mutations permit the emergence of full-blown cancer using IPSC models of childhood leukaemia

Primary supervisor: Tariq Enver, UCL Secondary supervisor: Charles Swanton, Francis Crick Institute/ UCL

Project 2: Germline predisposition to gene-specific somatic mutagenesis

Primary supervisor: Veronica Kinsler, Francis Crick Institute/ UCL

Project 3: Identifying the injury signals that drive early glioblastoma growth

Primary supervisor: Simona Parrinello, UCL Secondary supervisor: Samuel Marguerat, UCL

Project 1: Understanding and exploiting the impact of NPM1 mutations in reshaping the nucleolus of Acute Myeloid Leukaemia

Primary supervisor: Faraz Mardakheh, Queen Mary University of London Co-supervisors: Paolo Gallipoli, Queen Mary University of London, Beth Payne, UCL

Project 2: Dissecting the phenotype and function of sub-types of breast cancer associated fibroblasts (CAFs)

Primary supervisor: John Marshall, Queen Mary University of London Co-supervisor: J Louise Jones, Queen Mary University of London

Project 3: Investigating the impact of CDKN2A loss on lipid and sterol metabolism in ccRCC

Primary supervisor: Barry Peck, Queen Mary University of London Secondary supervisor: Samra Turajlic, Francis Crick Institute